WHY WE USE NANOTECHNOLOGY
WHAT IS A NANO-EMULSION?
A Nano-emulsion is a solution created by using mechanical force to break down active ingredients to a small enough size to be easily absorbed. Nanoparticles are so small that they can be absorbed into the blood stream efficiently and have been shown to dramatically increase the bioavailability of active compounds. Less needs to be consumed in order to experience effects. In addition, Nano-emulsification increases the speed of onset of the active ingredients. CANNAMISTNANO has applied this pharmaceutical technology to cannabis. Being comprised of water compatible molecules, it begins being absorbed as soon as it makes contact with your oral mucosa. The nano-sized cannabinoid particles are less than 22 nanometers in diameter, allowing them to effortlessly pass through the mucosal membranes resulting in fast onset. The cannabinoids are evenly distributed throughout the nano-emulsion, which ensures a consistent and predictable dose with every spray that provides 5-7 times more bioavailability of the active cannabinoids compared to other oral dosing systems.
HOW DOES IT COMPARE TO EDIBLES?
Edibles can be unpredictable in potency and time of onset. Oral delivery includes a liver first–pass effect where THC is metabolized by the liver into its main pharmacologically active metabolite, 11-hydroxy THC. This metabolite is similar to THC in that they are both psychoactive, but it is also more sedative. It has a longer half-life than THC, so the effects last longer. Processing an edible is dependent on what food has been consumed and also the condition of the liver. This results in unpredictable dosing and unpredictable onset that can be delayed up to 2 hours.
HOW DOES IT COMPARE TO INHALABLES?
The bioavailability of cannabis through the smoking route varies from 2 to 56%. This is due to the variability of smoking dynamics. Many consumers would prefer not to inhale but enjoy the fast onset of inhalables. With nano-technology, rapid onset is now possible in a non-inhalable product.
